Science-based nutrition
Dietary supplement
Supports healthy energy levels in heart and muscle tissue*
Maintains normal heart function*
Decreases free radical formation during exercise*
Suitable for Vegetarians
Ribose is an essential pentose (5-carbon) sugar utilized by the body to synthesize DNA,RNA and produce energy. (Ribose is a “sugar” distinct from glucose. It does not raise blood sugar levels or lead to diabetes.) Ribose is a fundamental building block of adenosine triphosphate (ATP - the substance in which the body stores intracellular energy), the preferential source of energy for skeletal muscle and heart tissue. Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism.* Further studies suggest that ribose plays a role in supporting energy recovery after exercise.* Exercise increases free radical production in muscle tissue. Ribose may strengthen and support the body's crucial antioxidant defenses.*
Research suggests that optimal heart function requires a consistent supply of essential cofactor nutrients including CoQ10, D-ribose, L-carnitine and Magnesium. Consider these other high quality Doctor’s Best products in combination with Best D-Ribose for enhanced cardiovascular support: High Absorption CoQ10, High Absorption Magnesium, Best L-Carnitine Fumarate
Use of BioEnergy Ribose™ is licensed by BioEnergy Life Science, Inc. under U.S. Patents 6,159,942; 6,534,480; 6,218,366; 6,339,716, and other U.S. and foreign patents issued and pending.
Supports Normal Heart Function*
A significant amount of in vitro, animal and human research suggests benefits of ribose on heart function.* Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism.* Ribose has been shown in clinical trials to enhance the recovery of heart muscle ATP levels and improve myocardial function following exercise.
Studies suggest that ribose supplementation can increase the tolerability of the cardiovascular system to exercise-induced fatigue.1 In one study, twenty men underwent treadmill exercise tests on two consecutive days to confirm the onset of fatigue secondary to exercise. The participants were then randomized to the treatment group or a placebo group. The groups received either four doses of 15 grams of D-ribose (60 grams/day total) or the same amount of placebo each day. After three days of treatment, another treadmill test was performed. The time it took to reach the specified level of fatigue was significantly greater in the ribose group than in the placebo group.
Another study investigated the ability of ribose to support healthy heart function and quality of life.2 In a randomized, crossover design study, fifteen individuals were given 5 grams three times a day of either D-ribose or placebo. Each treatment period lasted three weeks. In patients receiving ribose, echocardiography demonstrated enhancement of heart function, reflecting a “more efficient relaxation phase of the heart”. Participants also had a significant improvement in their subjective quality of life scores compared to placebo.
Scientists suggest that suboptimal heart function is a result of the heart requiring more energy to function properly. Ribose supports the heart’s enhanced energy requirements, promoting optimal heart function. It does so by enhancing the stores of high-energy phosphates in heart tissue. These intermediates are necessary for the production and resynthesis of ATP. A double-blind crossover study in which 12 individuals were randomized to receive either ribose or dextrose (both administered as 5 grams three times daily for three weeks, followed by a 1-week washout period and crossover of treatments for three additional weeks) suggested significant enhancements in normal cardiac function during the period of ribose supplementation.3
Perhaps one of the more useful illustrations of the potential for ribose to support heart function comes from a study in which 20 rats received a continuous infusion of ribose for 24 hours (control rats received an infusion of saline). The hearts were then explanted (as they would be for heart transplants) and placed in preservation solution that was enriched with ribose for 4 hours. ATP levels were measured from tissue biopsies and revealed that 10 of the ribose-treated hearts had ATP levels higher than 12.3 micromoles per gram whereas saline-treated hearts (controls) had lower ATP levels, with 20% showing levels below 10 micromoles per gram of tissue. This provides support for the hypothesis that ribose may enhance the preservation of ATP levels in cardiac tissue, promoting normal heart function.4
Ribose is an essential pentose (5-carbon) sugar utilized by the body to synthesize DNA, RNA and produce energy. Ribose is a fundamental building block of adenosine triphosphate (ATP – the substance in which the body stores intracellular energy), the preferential source of energy for skeletal muscle and heart tissue. Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism.* Further studies suggest that ribose plays a role in supporting energy recovery after exercise.* Exercise increases free radical production in muscle tissue. Ribose may strengthen and support the body’s crucial antioxidant defenses.*
